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The multiple locations of the long-chain acyl CoA synthetase reflect the location of different metabolic routes taken by fatty acyl CoA derivatives in the cell (e.g., triacylglycerol and phospholipid synthesis in the endoplasmic reticulum, oxidation and plasmalogen synthesis in the peroxisome, and β-oxidation in mitochondria)
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Targeted gene deletion of β 1 tubulin in mice results in thrombocytopenia and abnormal platelet and microtubule morphology
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