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For example, try to drink fewer liquids, particularly before you go out in public or go to bed avoid or limit alcohol and caffeine be physically active empty your bladder completely when you urinate use the restroom often and don’t try to hold urine for long periods of time avoid or monitor your use of medicines that can make BPH symptoms worse Medicines A health care professional may recommend medicines to treat your BPH such as alpha blockers, which relax the muscles in the bladder neck and prostate, making it easier to urinate 5-alpha reductase inhibitors (5-ARIs), which help stop the growth of or help shrink the prostate, improving your urine flow phosphodiesterase-5 inhibitors, which relax the muscles around the bladder, bladder neck, and prostate and can relieve some symptoms of BPH Research shows that a combination of an alpha blocker and a 5-ARI may work better than one medicine alone