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LCs are epidermal dendritic cells involved in maintaining the health and balance of the epidermis by regulating the adaptive immune responses to pathogen invasion [134,135]
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Besides, once 1,25(OH)2D enters the cell and interacts with the VDR to initiate its biological response, it simultaneously induces 25-hydroxyvitamin D-24-hydroxylase (CYP24A1)
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