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[DOI] [PubMed] [Google Scholar] [14].Chen B, Deng Y, Tan Y, Qin J, Chen LB, Association between severity of knee osteoarthritis and serum and synovial fluid interleukin 17 concentrations, J Int Med Res 42(1) (2014) 138–44
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A primary drawback of subcritical water extraction is the requirement for high temperatures, typically between 100°C and 374°C, which can cause thermal degradation of heat-sensitive polyphenolic compounds, thereby reducing their yield and bioactivity (66)
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