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These results support the hypothesis that neutrophils contribute to the ischemic oxidative stress as shown in (Jaeschke et al., Major functional classes of neutrophil proteome For the functional classification of the significantly regulated identified proteins, KEGG pathways, and Wikipathways databases were used as a reference knowledge base to understand various signaling mechanisms and pathways (Zhang and Wiemann, Rattus norvegicus genome as reference set for enrichment analysis using the online analysis WebGestalt (Wang et al., Five proteins from cluster 1 were found to be involved in antigen processing and presentation