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The redox status and activity of BiP will be of particular interest, given its roles in protein folding, ERAD, protein translocation, and UPR signaling (Pobre et al., 2019), and the fact that oxidative modifications can alter the nature of its associations with nascent proteins (Wang et al., 2014) and with the translocation channel (Ponsero et al., 2017)
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A new assay method for biotin in blood, serum, urine, and tissues
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